发明授权
- 专利标题: Functionalized nanoceria composition for ophthalmic treatment
- 专利标题(中): 用于眼科治疗的功能性纳米组合物
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申请号: US12147759申请日: 2008-06-27
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公开(公告)号: US07959949B2公开(公告)日: 2011-06-14
- 发明人: Sudipta Seal , Swanand D. Patil , Manas K. Haldar , Sanku Mallik
- 申请人: Sudipta Seal , Swanand D. Patil , Manas K. Haldar , Sanku Mallik
- 申请人地址: US FL Orlando
- 专利权人: University of Central Florida Research Foundation, Inc.
- 当前专利权人: University of Central Florida Research Foundation, Inc.
- 当前专利权人地址: US FL Orlando
- 代理机构: Allen, Dyer, Doppelt Milbrath & Gilchrist, P.A.
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61K33/24
摘要:
The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.
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