发明授权
- 专利标题： Protein formulations for use at elevated temperatures
- 专利标题（中）： 在高温下使用的蛋白质制剂
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申请号： US12695357申请日： 2010-01-28
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公开(公告)号： US07964561B2公开(公告)日： 2011-06-21
- 发明人: Venkata Garigapati , Dongling Su , Julius Lopez
- 申请人： Venkata Garigapati , Dongling Su , Julius Lopez
- 申请人地址： US MA Raynham
- 专利权人： Advanced Technologies and Regenerative Medicine, LLC
- 当前专利权人： Advanced Technologies and Regenerative Medicine, LLC
- 当前专利权人地址： US MA Raynham
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; A61K38/17 ; A61K38/18 ; C07H1/00
摘要：
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.
公开/授权文献
- US20100130730A1 PROTEIN FORMULATIONS FOR USE AT ELEVATED TEMPERATURES 公开/授权日：2010-05-27
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