发明授权
US07968713B2 Method of synthesizing quinoxaline derivative by microwave irradiation
失效
通过微波照射合成喹喔啉衍生物的方法
- 专利标题： Method of synthesizing quinoxaline derivative by microwave irradiation
- 专利标题（中）： 通过微波照射合成喹喔啉衍生物的方法
-
申请号： US11991799申请日： 2006-10-16
-
公开(公告)号： US07968713B2公开(公告)日： 2011-06-28
- 发明人: Toru Takabatake , Hiroaki Saito , Yusuke Sumiyoshi
- 申请人： Toru Takabatake , Hiroaki Saito , Yusuke Sumiyoshi
- 申请人地址： JP Tokyo
- 专利权人： Nihon University
- 当前专利权人： Nihon University
- 当前专利权人地址： JP Tokyo
- 代理机构： Morgan, Lewis & Bockius LLP
- 优先权： JP2005-300444 20051014
- 国际申请： PCT/JP2006/320560 WO 20061016
- 国际公布： WO2007/043680 WO 20070419
- 主分类号： C07D241/36
- IPC分类号： C07D241/36
摘要：
There is disclosed a method of synthesizing a quinoxaline derivative in which toxicity, corrosiveness and permeation are low and which is excellent in safety and which attains a reduced reaction time, a greatly improved yield and excellent economical efficiency. The object is achieved by a method of synthesizing a quinoxaline derivative which comprises adsorbing a benzofuroxan derivative and a β-diketone derivative on a solid support, and then heating the derivatives in a solid state by microwave irradiation to dehydrocyclize them. An example of a quinoxaline derivative is a compound of formula (4):