- 专利标题: Multi-cyclic cinnamide derivatives
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申请号: US13005064申请日: 2011-01-12
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公开(公告)号: US07973033B2公开(公告)日: 2011-07-05
- 发明人: Teiji Kimura , Noritaka Kitazawa , Toshihiko Kaneko , Nobuaki Sato , Koki Kawano , Koichi Ito , Eriko Doi , Mamoru Takaishi , Takeo Sasaki , Takehiko Miyagawa , Hiroaki Hagiwara , Takashi Doko
- 申请人: Teiji Kimura , Noritaka Kitazawa , Toshihiko Kaneko , Nobuaki Sato , Koki Kawano , Koichi Ito , Eriko Doi , Mamoru Takaishi , Takeo Sasaki , Takehiko Miyagawa , Hiroaki Hagiwara , Takashi Doko
- 申请人地址: JP Tokyo
- 专利权人: Eisai R&D Management Co., Ltd.
- 当前专利权人: Eisai R&D Management Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: JP2006-063562 20060309; JP2006-322728 20061130
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; C07D498/04 ; A61K31/5383 ; A61K31/5025
摘要:
The present invention provides a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, Ar2 represents a phenyl group that may be substituted with a C1-6 alkoxy group, or the like, X1 represents a double bond or the like, and Het represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, which is effective as a therapeutic or prophylactic agent for a disease caused by Aβ.
公开/授权文献
- US20110112138A1 MULTI-CYCLIC CINNAMIDE DERIVATIVES 公开/授权日:2011-05-12
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