发明授权
- 专利标题： Bacillus subtilis mutant strain
- 专利标题（中）： 枯草芽孢杆菌突变菌株
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申请号： US12083539申请日： 2006-09-25
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公开(公告)号： US07981659B2公开(公告)日： 2011-07-19
- 发明人: Ryosuke Kadoya , Keiji Endo , Masatoshi Tohata , Katsutoshi Ara , Naotake Ogasawara
- 申请人： Ryosuke Kadoya , Keiji Endo , Masatoshi Tohata , Katsutoshi Ara , Naotake Ogasawara
- 申请人地址： JP Tokyo JP Nara
- 专利权人： Kao Corporation,Nara Institute of Science and Technology
- 当前专利权人： Kao Corporation,Nara Institute of Science and Technology
- 当前专利权人地址： JP Tokyo JP Nara
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权： JP2005-298406 20051013
- 国际申请： PCT/JP2006/318986 WO 20060925
- 国际公布： WO2007/043327 WO 20070419
- 主分类号： C12N1/20
- IPC分类号： C12N1/20
摘要：
Novel Bacillus subtilis mutant strains having good productivity of various enzymes are provided through extensive analysis of strains that are derived from Bacillus subtilis via gene disruption. The Bacillus subtilis mutant strains according to the present invention have genomic structures prepared by deletion of regions listed in the columns for deficient regions. Each of these Bacillus subtilis mutant strains exerts significantly improved secretory productivity of a protein when a gene encoding such a secretory target protein is introduced so that it can be expressed, compared with a case in which the same gene is introduced into a wild-type strain.
公开/授权文献
- US20090221055A1 Novel Bacillus Subtilis Mutant Strain 公开/授权日：2009-09-03
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