发明授权
- 专利标题： Methods and compositions for monitoring and risk prediction in cardiorenal syndrome
- 专利标题（中）： 心脏综合征监测和风险预测的方法和组成
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申请号： US12909654申请日： 2010-10-21
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公开(公告)号： US07985560B2公开(公告)日： 2011-07-26
- 发明人: Gunars Valkirs , Paul H. McPherson
- 申请人： Gunars Valkirs , Paul H. McPherson
- 申请人地址： US CA San Diego
- 专利权人： Alere San Diego, Inc.
- 当前专利权人： Alere San Diego, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Wilson Sonsini Goodrich & Rosati
- 主分类号： G01N1/00
- IPC分类号： G01N1/00 ; G01N33/53
摘要：
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods and compositions selected to monitor cardiorenal syndrome using assays that detect NGAL, preferably together with assays that detect natriuretic peptides such as BNP. Such methods and compositions can provide early indications of a deterioration in cardiorenal syndrome status, including prognosis regarding mortality and worsening renal function.
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