A design structure embodied in a machine readable storage medium for at designing, manufacturing, and/or testing a design is disclosed for initializing expansion adapters installed in a computer system having similar expansion adapters that include detecting an expansion adapter installed in a computer system having a plurality of expansion adapters, the detected expansion adapter having an option ROM containing initialization code, identifying similar expansion adapters installed in the computer system that correspond to the detected expansion adapter, each of the identified similar expansion adapters having an option ROM containing initialization code, disabling the option ROM of each of the identified similar expansion adapters, and initializing the plurality of expansion adapters installed in the computer system without executing the initialization code of the identified similar expansion adapters.