发明授权
- 专利标题： Soluble fusion proteins comprising heterologous polypeptides
- 专利标题（中）： 包含异源多肽的可溶性融合蛋白
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申请号： US12379808申请日： 2009-03-02
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公开(公告)号： US07989183B2公开(公告)日： 2011-08-02
- 发明人: Nathan Nelson , Anat Lavi-Itzkovitz , Shani Leviatan
- 申请人： Nathan Nelson , Anat Lavi-Itzkovitz , Shani Leviatan
- 申请人地址： IL Tel-Aviv
- 专利权人： Ramot at Tel-Aviv University Ltd.
- 当前专利权人： Ramot at Tel-Aviv University Ltd.
- 当前专利权人地址： IL Tel-Aviv
- 主分类号： C07K19/00
- IPC分类号： C07K19/00 ; C12N15/62
摘要：
A soluble fusion protein is disclosed. The soluble fusion protein comprises at least one soluble polypeptide and a heterologous polypeptide being fused thereto, the heterologous polypeptide being normally insoluble and/or suboptimally expressed when expressed in a cell, wherein the at least one soluble polypeptide has an amino acid sequence at least 65 percent similar to SEQ ID NO: 1 and/or 2, as determined using the Standard protein-protein BLAST [blastp] software of the NCBI.
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