发明授权
- 专利标题： Chimeric NK receptor and methods for treating cancer
- 专利标题（中）： 嵌合NK受体和治疗癌症的方法
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申请号： US11575878申请日： 2005-08-31
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公开(公告)号： US07994298B2公开(公告)日： 2011-08-09
- 发明人: Tong Zhang , Charles L. Sentman
- 申请人： Tong Zhang , Charles L. Sentman
- 申请人地址： US NH Hanover
- 专利权人： Trustees of Dartmouth College
- 当前专利权人： Trustees of Dartmouth College
- 当前专利权人地址： US NH Hanover
- 代理机构： Hunton & Williams LLP
- 国际申请： PCT/US2005/031100 WO 20050831
- 国际公布： WO2006/036445 WO 20060406
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C12N15/63 ; C12N15/85
摘要：
The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
公开/授权文献
- US20100029749A1 Chimeric NK Receptor and Methods for Treating Cancer 公开/授权日：2010-02-04
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