发明授权
- 专利标题: Degradable clostridial toxins
- 专利标题(中): 可降解梭菌毒素
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申请号: US12192905申请日: 2008-08-15
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公开(公告)号: US07998489B2公开(公告)日: 2011-08-16
- 发明人: Lance E. Steward , Ester G. Fernandez-Salas , Marcella A. Gilmore , Joseph Francis , Shengwen Li , Kei Roger Aoki
- 申请人: Lance E. Steward , Ester G. Fernandez-Salas , Marcella A. Gilmore , Joseph Francis , Shengwen Li , Kei Roger Aoki
- 申请人地址: US CA Irvine
- 专利权人: Allergan, Inc.
- 当前专利权人: Allergan, Inc.
- 当前专利权人地址: US CA Irvine
- 代理商 Kenton Abel; Debra Condino
- 主分类号: C07K14/00
- IPC分类号: C07K14/00 ; C07K14/33 ; C07H21/04
摘要:
The specification discloses modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; polynucleotide molecules encoding modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; and method of producing modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain.
公开/授权文献
- US20090023901A1 Degradable Clostridial Toxins 公开/授权日:2009-01-22
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