Invention Grant
- Patent Title: Affinity adsorbents for plasminogen
- Patent Title (中): 纤溶酶原亲和吸附剂
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Application No.: US11913514Application Date: 2006-05-09
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Publication No.: US07998960B2Publication Date: 2011-08-16
- Inventor: Jason Richard Betley , James Christopher Pearson , Claudia Hildegard Kuhn , Baldev Singh Baines
- Applicant: Jason Richard Betley , James Christopher Pearson , Claudia Hildegard Kuhn , Baldev Singh Baines
- Applicant Address: IM Ballasalla
- Assignee: Prometic Biosciences Ltd.
- Current Assignee: Prometic Biosciences Ltd.
- Current Assignee Address: IM Ballasalla
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: GB0509438.8 20050509
- International Application: PCT/GB2006/001686 WO 20060509
- International Announcement: WO2006/120423 WO 20061116
- Main IPC: A01N43/66
- IPC: A01N43/66 ; C07H19/12 ; C07K16/06 ; A61K39/395

Abstract:
For the separation, removal, isolation, purification, characterization, identification or quantification of plasminogen or a protein that is a plasminogen analogue, an affinity adsorbent is used that is a compound of formula (II) wherein one X is N and the other is N, C—Cl or C—CN; A is a support matrix, optionally linked to the triazine ring by a spacer; Z is O, S or N—R and R is H, C1-6 alkyl, C1-6 hydroxyalkyl, benzyl or &bgr;-phenylethyl; B is an optionally substituted hydrocarbon linkage containing from 1 to 10 carbon atoms; D is H, OH or a primary amino, secondary amino, tertiary amino, quaternary ammonium, imidazole, guanidino or amidino group; or B-D is —CHCOOH—(CH2)3-4—NH2; and q is 2 to 6.
Public/Granted literature
- US20080293925A1 Affinity Adsorbents for Plasminogen Public/Granted day:2008-11-27
Information query
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