发明授权
- 专利标题： Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
- 专利标题（中）： 嘧啶环戊烷作为AKT蛋白激酶抑制剂
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申请号： US11773946申请日： 2007-07-05
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公开(公告)号： US08003651B2公开(公告)日： 2011-08-23
- 发明人: Ian S. Mitchell , James F. Blake , Rui Xu , Nicholas C. Kallan , Dengming Xiao , Keith Lee Spencer , Josef R. Bencsik , Eli M. Wallace , Stephen T. Schlachter , Anna L. Banka , Jun Liang , Brian Safina , Jun Li , Christine Chabot
- 申请人： Ian S. Mitchell , James F. Blake , Rui Xu , Nicholas C. Kallan , Dengming Xiao , Keith Lee Spencer , Josef R. Bencsik , Eli M. Wallace , Stephen T. Schlachter , Anna L. Banka , Jun Liang , Brian Safina , Jun Li , Christine Chabot
- 申请人地址： US CO Boulder US CA South San Francisco
- 专利权人： Array BioPharma Inc.,Genertech, Inc.
- 当前专利权人： Array BioPharma Inc.,Genertech, Inc.
- 当前专利权人地址： US CO Boulder US CA South San Francisco
- 代理机构： Viksnins Harris & Padys PLLP
- 主分类号： C07D239/70
- IPC分类号： C07D239/70 ; A61K31/497 ; A61P35/00 ; A61P29/00 ; A61P25/28 ; A61P9/00
摘要：
The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
公开/授权文献
- US20080058327A1 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS 公开/授权日：2008-03-06
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