发明授权
- 专利标题: Therapeutic agents useful for treating pain
- 专利标题(中): 用于治疗疼痛的治疗剂
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申请号: US12499480申请日: 2009-07-08
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公开(公告)号: US08008300B2公开(公告)日: 2011-08-30
- 发明人: Qun Sun , Laykea Tafesse , Sam Victory
- 申请人: Qun Sun , Laykea Tafesse , Sam Victory
- 申请人地址: US CT Stamford
- 专利权人: Purdue Pharma L.P.
- 当前专利权人: Purdue Pharma L.P.
- 当前专利权人地址: US CT Stamford
- 代理机构: Dechert LLP
- 主分类号: A61K31/50
- IPC分类号: A61K31/50 ; A61K31/497 ; C07D403/04 ; C07D241/02
摘要:
A compound of formula: wherein Ar1, A, R3, x, and m are as disclosed herein and Ar2 is a benzothiazolyl, benzooxazolyl, or benzoimidazolyl group or a pharmaceutically acceptable salt thereof (a “Benzoazolylpiperazine Compound”), compositions comprising a Benzoazolylpiperazine Compound, and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Benzoazolylpiperazine Compound are disclosed.
公开/授权文献
- US20100004254A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN 公开/授权日:2010-01-07
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