发明授权
US08012988B2 N-(2,4-dioxo-6-(tetrahydrofuran-2-yl)-7-(trifluoromethyl)-1,4-dihydro-2H-quinazolin-3-yl)methanesulfonamide
失效
N-（2,4-二氧代-6-（四氢呋喃-2-基）-7-（三氟甲基）-1,4-二氢-2H-喹唑啉-3-基）甲磺酰胺
- 专利标题： N-(2,4-dioxo-6-(tetrahydrofuran-2-yl)-7-(trifluoromethyl)-1,4-dihydro-2H-quinazolin-3-yl)methanesulfonamide
- 专利标题（中）： N-（2,4-二氧代-6-（四氢呋喃-2-基）-7-（三氟甲基）-1,4-二氢-2H-喹唑啉-3-基）甲磺酰胺
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申请号： US12569402申请日： 2009-09-29
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公开(公告)号： US08012988B2公开(公告)日： 2011-09-06
- 发明人: Hans Allgeier , Yves Auberson , David Carcache , Philipp Floersheim , Christel Guibourdenche , Wolfgang Froestl , Jörg Kallen , Manuel Koller , Henri Mattes , Joachim Nozulak , David Orain , Johanne Renaud
- 申请人： Hans Allgeier , Yves Auberson , David Carcache , Philipp Floersheim , Christel Guibourdenche , Wolfgang Froestl , Jörg Kallen , Manuel Koller , Henri Mattes , Joachim Nozulak , David Orain , Johanne Renaud
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理机构： Strain & Strain PLLC
- 代理商 Paul D. Strain
- 优先权： GB0507298.8 20050411
- 主分类号： A61K31/517
- IPC分类号： A61K31/517
摘要：
The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
公开/授权文献
- US20100144747A1 1H-QUINAZ0LINE-2,4-DIONES 公开/授权日：2010-06-10
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