Invention Grant
- Patent Title: Method for producing alcohol by hydrogenating lactone and carboxylic acid ester in liquid phase
- Patent Title (中): 通过在液相中氢化内酯和羧酸酯来生产醇的方法
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Application No.: US12594577Application Date: 2008-04-02
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Publication No.: US08013193B2Publication Date: 2011-09-06
- Inventor: Hirofumi Maeda , Kenji Inoue , Takaji Matsumoto , Izuru Nagasaki , Ryoji Noyori , Susumu Saito
- Applicant: Hirofumi Maeda , Kenji Inoue , Takaji Matsumoto , Izuru Nagasaki , Ryoji Noyori , Susumu Saito
- Applicant Address: JP Osaka JP Tokyo
- Assignee: Kaneka Corporation,Takasago International Corporation
- Current Assignee: Kaneka Corporation,Takasago International Corporation
- Current Assignee Address: JP Osaka JP Tokyo
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Peter F. Corless; Christine C. O'Day
- Priority: JP2007-097618 20070403
- International Application: PCT/JP2008/000850 WO 20080402
- International Announcement: WO2008/120475 WO 20081009
- Main IPC: C07C29/149
- IPC: C07C29/149

Abstract:
Disclosed is a method for producing an alcohol from a lactone or a carboxylic acid ester, which enables to produce an alcohol from a lactone or a carboxylic acid ester under relatively mild conditions with high yield and high catalytic efficiency. This method also enables to produce an optically active alcohol from an optically active lactone or an optically active carboxylic acid ester. Specifically disclosed is a method for producing an alcohol by hydrogen reducing a lactone or a carboxylic acid ester in the presence of a catalyst containing ruthenium and a phosphine compound represented by the following general formula (1): wherein R1 represents a spacer; R2, R3, R4, R5, R6 and R7 independently represent a hydrogen atom, an alkyl group having 1-12 carbon atoms, an aryl group or a heterocyclic group; and R8, R9, R10, R11, R12 and R13 independently represent an alkyl group having 1-12 carbon atoms, an aryl group or a heterocyclic group.
Public/Granted literature
- US20100113842A1 METHOD FOR PRODUCING ALCOHOL BY HYDROGENATING LACTONE AND CARBOXYLIC ACID ESTER IN LIQUID PHASE Public/Granted day:2010-05-06
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