Invention Grant
- Patent Title: Tumor-inhibiting protein and the use thereof
- Patent Title (中): 肿瘤抑制蛋白及其用途
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Application No.: US12171112Application Date: 2008-07-10
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Publication No.: US08030015B2Publication Date: 2011-10-04
- Inventor: Mujun Zhao , Zhenhua Xu , Liang Liang , Zaiping Li
- Applicant: Mujun Zhao , Zhenhua Xu , Liang Liang , Zaiping Li
- Applicant Address: CN Shanghai
- Assignee: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Current Assignee: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Current Assignee Address: CN Shanghai
- Agency: Osha • Liang LLP
- Priority: CN03116920 20030514
- Main IPC: G01N33/574
- IPC: G01N33/574
Abstract:
The invention has disclosed a new tumor suppressor protein HCRP1, the polynucleotide sequences encoding this polypeptides, and methods for production of the polypeptide using the recombinant technology. The tumor suppression protein, HCRP1, is obtained through the positional candidate cloning strategy. It locates in 8p22 region of human chromosome. The full length cDNA for HCRP1 is 1916 bp, which encodes a protein of 397 amino acids. When introduced into liver cancer cells, HCRP1 can inhibit the malignant transformation of liver cancer cells.
Public/Granted literature
- US20090143290A1 TUMOR-INHIBITING PROTEIN AND THE USE THEREOF Public/Granted day:2009-06-04
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