发明授权
- 专利标题： 2′-hydroxyl group-modified ribonucleoside derivatives
- 专利标题（中）： 2'-羟基修饰的核糖核苷衍生物
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申请号： US12224677申请日： 2007-03-08
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公开(公告)号： US08039611B2公开(公告)日： 2011-10-18
- 发明人: Mitsuo Sekine , Takeshi Yamada , Hisao Saneyoshi , Kohji Seio
- 申请人： Mitsuo Sekine , Takeshi Yamada , Hisao Saneyoshi , Kohji Seio
- 申请人地址： JP Tokyo
- 专利权人： Tokyo Institute of Technology
- 当前专利权人： Tokyo Institute of Technology
- 当前专利权人地址： JP Tokyo
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JP2006-063358 20060308
- 国际申请： PCT/JP2007/054533 WO 20070308
- 国际公布： WO2007/102581 WO 20070913
- 主分类号： C07H21/00
- IPC分类号： C07H21/00
摘要：
Provided is a ribonucleoside derivative represented by General Formula (I): (wherein R1 represents a hydrogen atom or the like, R2 represents a hydrogen atom or the like, R3 represents a methyl group or the like, and B represents a nucleic acid base residue optionally having a protecting group or a modifying group). An RNA containing this ribonucleoside derivative shows excellent hybridization ability and resistance to nuclease.
公开/授权文献
- US20100016574A1 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives 公开/授权日：2010-01-21
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