发明授权
- 专利标题： Method of screening for agents to treat heart failure
- 专利标题（中）： 筛查治疗心力衰竭的药物的方法
-
申请号： US12313539申请日： 2008-11-22
-
公开(公告)号： US08043801B2公开(公告)日： 2011-10-25
- 发明人: Jeanne Y. Wei , Gohar Azhar , Xiaomin Zhang
- 申请人： Jeanne Y. Wei , Gohar Azhar , Xiaomin Zhang
- 申请人地址： US AR Little Rock
- 专利权人： Jeanne Y. Wei
- 当前专利权人： Jeanne Y. Wei
- 当前专利权人地址： US AR Little Rock
- 代理商 Hugh McTavish
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00 ; C12Q1/68 ; A61K48/00 ; C07H21/04
摘要：
The invention provides a method of identifying candidate agents to test for treating heart failure involving diastolic impairment, the method comprising: testing an agent to determine whether it (a) binds to serum response factor (SRF), (b) reduces SRF binding to a serum response element (SRE), or (c) reduces SRF protein levels in a cell; wherein if the agent does one or more of (a), (b), and (c), it is identified as a candidate agent.
公开/授权文献
- US20090187998A1 Method of screening for agents to treat heart failure 公开/授权日：2009-07-23
信息查询
