发明授权
- 专利标题： Fused heterocyclic derivative and use thereof
- 专利标题（中）： 熔融杂环衍生物及其用途
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申请号： US12064903申请日： 2007-08-03
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公开(公告)号： US08044049B2公开(公告)日： 2011-10-25
- 发明人: Nozomu Sakai , Shinichi Imamura , Naoki Miyamoto , Takaharu Hirayama
- 申请人： Nozomu Sakai , Shinichi Imamura , Naoki Miyamoto , Takaharu Hirayama
- 申请人地址： JP Osaka
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Osaka
- 代理机构： Hamre, Schumann, Mueller & Larson, P.C.
- 优先权： JP2006-213981 20060804; JP2006-331230 20061207; JP2007-144072 20070530
- 国际申请： PCT/JP2007/065681 WO 20070803
- 国际公布： WO2008/016192 WO 20080207
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/5025 ; A61P35/00
摘要：
The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof.A compound represented by the formula (I): wherein each symbol is as defined in the specification, except a particular compound, or a salt thereof, and a pharmaceutical agent containing the compound or a prodrug thereof, which is a kinase (VEGFR, VEGFR2, PDGFR, Raf) inhibitor, an angiogenesis inhibitor, an agent for the prophylaxis or treatment of cancer, a cancer growth inhibitor or a cancer metastasis suppressor.
公开/授权文献
- US20090137595A1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF 公开/授权日：2009-05-28
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