Invention Grant
US08044062B2 Substituted pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors of phospatidylinositol 3-kinase alpha
有权
取代的吡啶并[2,3-d]嘧啶-7(8H) - 酮磷酸肌醇3-激酶α抑制剂
- Patent Title: Substituted pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors of phospatidylinositol 3-kinase alpha
- Patent Title (中): 取代的吡啶并[2,3-d]嘧啶-7(8H) - 酮磷酸肌醇3-激酶α抑制剂
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Application No.: US11988848Application Date: 2006-10-09
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Publication No.: US08044062B2Publication Date: 2011-10-25
- Inventor: Tae-Gon Baik , Chris A. Buhr , Katherine Lara , Sunghoon Ma , Morrison Mac , John M. Nuss , Longcheng Wang , Yong Wang , Bryan K. S. Yeung
- Applicant: Tae-Gon Baik , Chris A. Buhr , Katherine Lara , Sunghoon Ma , Morrison Mac , John M. Nuss , Longcheng Wang , Yong Wang , Bryan K. S. Yeung
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Honigman Miller Schwartz & Cohn LLP
- Agent Heidi M. Berven; Jonathan P. O'Brien
- International Application: PCT/US2006/039734 WO 20061009
- International Announcement: WO2007/044813 WO 20070419
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/519 ; A61P35/00
![Substituted pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors of phospatidylinositol 3-kinase alpha](/abs-image/US/2011/10/25/US08044062B2/abs.jpg.150x150.jpg)
Abstract:
The invention is directed to Compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.
Public/Granted literature
- US20090270430A1 Pyridopyrimidinone Inhibitors of Pl3Kalpha Public/Granted day:2009-10-29
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