An application-specific integrated circuit (ASIC) comprising a plurality of channels, each channel having circuitry for time and energy discrimination, a plurality of programmable registers, each programmable register configured to output at least one configuration parameter for the circuitry, and a channel-select register configured to identify a channel of the plurality of channels to be configured. The ASIC further includes a configuration-select register configured to identify the programmable register to be used for channel configuration, and a communications interface configured to transmit instructions received from a controller to one of the channel-select register, the configuration-select register, and the plurality of programmable registers.