发明授权
US08048901B2 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups, processes for their preparation and their use as pharmaceuticals
有权
具有酸性,主要是杂环基团的1,3-取代的环烷基衍生物,其制备方法及其作为药物的用途
- 专利标题: 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups, processes for their preparation and their use as pharmaceuticals
- 专利标题(中): 具有酸性,主要是杂环基团的1,3-取代的环烷基衍生物,其制备方法及其作为药物的用途
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申请号: US11775564申请日: 2007-07-10
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公开(公告)号: US08048901B2公开(公告)日: 2011-11-01
- 发明人: Jochen Goerlitzer , Heiner Glombik , Eugen Falk , Dirk Gretzke , Stefanie Keil , Hans-Ludwig Schaefer , Christian Stapper , Wolfgang Wendler
- 申请人: Jochen Goerlitzer , Heiner Glombik , Eugen Falk , Dirk Gretzke , Stefanie Keil , Hans-Ludwig Schaefer , Christian Stapper , Wolfgang Wendler
- 申请人地址: DE Frankfurt am Main
- 专利权人: Aventis Pharma Deutschland GmbH
- 当前专利权人: Aventis Pharma Deutschland GmbH
- 当前专利权人地址: DE Frankfurt am Main
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 优先权: DE10308351 20030227
- 主分类号: A61K31/421
- IPC分类号: A61K31/421 ; C07D263/34
摘要:
The invention relates to 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups and to their physiologically acceptable salts and physiologically functional derivatives.What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved.
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