A self-tapping screw having a boring part and a threaded shaft for fixing a panel-type object to a preferably metallic substructure is provided. The screw is configured in such a way that it produces a through hole in the panel type object, said hole accommodating the shaft with a degree of play and so that it produces a bore in the substructure into which the thread on the shaft cuts a counter-thread. The boring part includes a boring tip that is located eccentrically in relation to the longitudinal axis of the screw. The tip centers the screw during the positioning operation in such a way that the boring part executes a circular displacement about the boring tip, which expands the through hole to the desired size, whereas the bore in the substructure is produced with the diameter of the boring part. The screw replaces self-tapping screws provided with boring flights and is preferably for use with a substructure consisting of thin sheet metal through which the boring flights of conventional screws can inadvertently penetrate.