发明授权
- 专利标题: Cyclic hydroxylamine as psychoactive compounds
- 专利标题(中): 循环羟胺作为精神活性化合物
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申请号: US12801568申请日: 2010-06-15
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公开(公告)号: US08053432B2公开(公告)日: 2011-11-08
- 发明人: Phillip Parsons , Silvia Trasciatti , Sergio Rosini , Michael Annis
- 申请人: Phillip Parsons , Silvia Trasciatti , Sergio Rosini , Michael Annis
- 申请人地址: GB London
- 专利权人: BTG International Limited
- 当前专利权人: BTG International Limited
- 当前专利权人地址: GB London
- 代理机构: Nixon & Vanderhye
- 优先权: GB0313628.0 20030612; GB0328439.5 20031208
- 主分类号: A61K31/535
- IPC分类号: A61K31/535
摘要:
A compound of formula (I): in which X represents O or CH2; R3 and R4 each independently represent hydrogen or C1-6 alkyl; p represent 0 or 1; and R represents a five- or six-membered saturated or unsaturated ring selected from: formula (II), (III) and (IV); or R represents a five- or six-membered oxo-substituted unsaturated ring selected from: (V) and (VI); wherein R1 and R2 together represent an oxo group, or R1 and R2 each represent hydrogen, methoxy or ethoxy, or R1 and R2 together with the interjacent carbon atom represent a 1,3-dioxolane or 1,3-dioxane ring, attached via the 2 position and optionally bearing one or more methyl or ethyl groups; or a salt thereof, is suitable for the treatment of anxiety and depression.
公开/授权文献
- US20100256150A1 Cyclic hydroxylamine as psychoactive compounds 公开/授权日:2010-10-07
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