发明授权
- 专利标题： Substituted triphenyl butenes
- 专利标题（中）： 取代的三苯基丁烯
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申请号： US12429128申请日： 2009-04-23
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公开(公告)号： US08063249B1公开(公告)日： 2011-11-22
- 发明人: Peter Kushner , Cyrus Harmon , David Myles
- 申请人： Peter Kushner , Cyrus Harmon , David Myles
- 申请人地址： US CA San Francisco
- 专利权人： Olema Pharmaceuticals, Inc.
- 当前专利权人： Olema Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Francisco
- 代理机构： King & Spalding LLP
- 代理商 Margaret B. Brivanlou
- 主分类号： C07C215/46
- IPC分类号： C07C215/46 ; C07C217/54 ; A61K31/133
摘要：
The present invention is directed to compounds, compositions thereof, and the use of the compounds and compositions for the treatment and prevention of breast cancer. In one embodiment, the present invention relates to the use of a substituted triphenyl butene or prodrug thereof for the treatment of breast cancer in mono-therapy or in combination therapy, or for a reduction in the recurrence rate of previously-treated breast cancer.
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