发明授权
- 专利标题： VMP-like sequences of pathogenic Borrelia
- 专利标题（中）： VMP样序列的致病性疏螺旋体
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申请号： US12853019申请日： 2010-08-09
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公开(公告)号： US08071109B2公开(公告)日： 2011-12-06
- 发明人: Steven J. Norris , Jing-Ren Zhang , John M. Hardham , Jerrilyn K. Howell , Alan G. Barbour , George M. Weinstock
- 申请人： Steven J. Norris , Jing-Ren Zhang , John M. Hardham , Jerrilyn K. Howell , Alan G. Barbour , George M. Weinstock
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 代理机构： Fulbright & Jaworski LLP
- 主分类号： A61K39/02
- IPC分类号： A61K39/02 ; A61K39/00 ; A61K39/38
摘要：
The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
公开/授权文献
- US20100317026A1 VMP-Like Sequences Of Pathogenic Borrelia 公开/授权日：2010-12-16