发明授权
US08078268B2 System and method of chemical imaging using pulsed laser excitation and time-gated detection to determine tissue margins during surgery
有权
使用脉冲激光激发和时间门控检测的化学成像的系统和方法来确定手术期间的组织边缘
- 专利标题： System and method of chemical imaging using pulsed laser excitation and time-gated detection to determine tissue margins during surgery
- 专利标题（中）： 使用脉冲激光激发和时间门控检测的化学成像的系统和方法来确定手术期间的组织边缘
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申请号： US12565279申请日： 2009-09-23
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公开(公告)号： US08078268B2公开(公告)日： 2011-12-13
- 发明人: John S. Maier , Shona Stewart , Jeffrey Cohen , Matthew Nelson , Patrick J Treado
- 申请人： John S. Maier , Shona Stewart , Jeffrey Cohen , Matthew Nelson , Patrick J Treado
- 申请人地址： US PA Pittsburgh
- 专利权人： ChemImage Corporation
- 当前专利权人： ChemImage Corporation
- 当前专利权人地址： US PA Pittsburgh
- 主分类号： A61B6/00
- IPC分类号： A61B6/00
摘要：
System and method for differentiating tissue margins in a biological sample using pulsed laser excitation and time-gated detection. A region containing a biological tissue is irradiated with substantially monochromatic pulsed laser light to thereby produce Raman scattered photons. The Raman scattered photons are detected using time-gated detection to thereby obtain a Raman spectroscopic image from the irradiated region characteristic of either a neoplastic portion or a non-neoplastic portion of the region containing the biological tissue. A boundary between a neoplastic portion and a non-neoplastic portion is differentiated and the boundary location in the Raman spectroscopic image is displayed.
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