发明授权
- 专利标题: Long lasting synthetic exendin-4 peptide conjugates
- 专利标题(中): 持久的合成毒蜥外泌肽-4肽缀合物
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申请号: US11170967申请日: 2005-06-29
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公开(公告)号: US08080516B2公开(公告)日: 2011-12-20
- 发明人: Dominique P. Bridon , Benoit L'Archeveque , Darren L. Holmes , Anouk LeBlanc , Serge St. Pierre
- 申请人: Dominique P. Bridon , Benoit L'Archeveque , Darren L. Holmes , Anouk LeBlanc , Serge St. Pierre
- 申请人地址: US CA Los Angeles
- 专利权人: Conjuchem, LLC
- 当前专利权人: Conjuchem, LLC
- 当前专利权人地址: US CA Los Angeles
- 代理机构: Morrison & Foerster LLP
- 主分类号: A61K38/22
- IPC分类号: A61K38/22
摘要:
Modified insulinotropic peptides are disclosed. The modified insulinotropic peptides are capable of forming a peptidase stabilized insulinotropic peptide. The modified insulinotropic peptides are capable of forming covalent bonds with one or more blood components to form a conjugate. The conjugates may be formed in vivo or ex vivo. The modified peptides are administered to treat humans with diabetes and other related diseases.
公开/授权文献
- US20060009377A1 Long lasting synthetic glucagon like peptide (GLP-1) 公开/授权日:2006-01-12