发明授权
US08088886B2 Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
失效
脂蛋白相关磷脂酶A2,其抑制剂及其在诊断和治疗中的应用
- 专利标题: Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
- 专利标题(中): 脂蛋白相关磷脂酶A2,其抑制剂及其在诊断和治疗中的应用
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申请号: US10406156申请日: 2003-04-02
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公开(公告)号: US08088886B2公开(公告)日: 2012-01-03
- 发明人: Colin Houston MacPhee , David Graham Tew
- 申请人: Colin Houston MacPhee , David Graham Tew
- 申请人地址: GB Middlesex
- 专利权人: Smith-Kline Beecham P.L.C.
- 当前专利权人: Smith-Kline Beecham P.L.C.
- 当前专利权人地址: GB Middlesex
- 代理机构: Licata & Tyrrell P.C.
- 代理商 Keith R. McCollum
- 优先权: GB9313144.9 19930625; GB9400413.2 19940111
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/04 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00
摘要:
The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
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