发明授权
- 专利标题: Methods for use in human-adapting monoclonal antibodies
- 专利标题(中): 用于人类适应性单克隆抗体的方法
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申请号: US11924094申请日: 2007-10-25
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公开(公告)号: US08093068B2公开(公告)日: 2012-01-10
- 发明人: Shizhong Chen , Shanrong Zhao
- 申请人: Shizhong Chen , Shanrong Zhao
- 申请人地址: US PA Malvern
- 专利权人: Centocor, Inc.
- 当前专利权人: Centocor, Inc.
- 当前专利权人地址: US PA Malvern
- 代理商 Kirk Baumeister
- 主分类号: G01N33/536
- IPC分类号: G01N33/536 ; G01N33/531 ; C07K16/00
摘要:
Methods useful for human adapting non-human monoclonal antibodies are disclosed. The methods select candidate human antibody framework sequences from a human germline framework database.
公开/授权文献
- US20090137403A1 METHODS FOR USE IN HUMAN-ADAPTING MONOCLONAL ANTIBODIES 公开/授权日:2009-05-28
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