- 专利标题: Optimized Fc variants and methods for their generation
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申请号: US11981822申请日: 2007-10-31
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公开(公告)号: US08093359B2公开(公告)日: 2012-01-10
- 发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
- 申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
- 申请人地址: US CA Monrovia
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: US CA Monrovia
- 代理机构: Morgan Lewis & Bockius LLP
- 代理商 Robin M. Silva, Esq.; Ada O. Wong, Esq.
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C07K14/00 ; C12P21/08
摘要:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
公开/授权文献
- US20090068177A1 Optimized Fc variants and methods for their generation 公开/授权日:2009-03-12
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