发明授权
- 专利标题： Peptides that block the binding of IgG to FcRn
- 专利标题（中）： 阻断IgG与FcRn结合的肽
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申请号： US11676148申请日： 2007-02-16
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公开(公告)号： US08101186B2公开(公告)日： 2012-01-24
- 发明人: Adam R. Mezo , Kevin A. McDonnell , Cristina A. Tan Hehir , Alfredo Castro
- 申请人： Adam R. Mezo , Kevin A. McDonnell , Cristina A. Tan Hehir , Alfredo Castro
- 申请人地址： US MA Waltham
- 专利权人： Syntonix Pharmaceuticals, Inc.
- 当前专利权人： Syntonix Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Waltham
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/08 ; A61K38/10 ; A61K38/16
摘要：
The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates to methods of using and methods of making the peptides of the invention.
公开/授权文献
- US20070254831A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn 公开/授权日：2007-11-01
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