发明授权
- 专利标题: Detection of ESR1 amplification in breast cancer
- 专利标题(中): 检测乳腺癌中ESR1扩增
-
申请号: US12305258申请日: 2007-06-26
-
公开(公告)号: US08101352B2公开(公告)日: 2012-01-24
- 发明人: Guido Sauter , Ronald Simon , Phillip Stahl , Frederik Holst , Khawla Al-Kuraya , Christian Ruiz
- 申请人: Guido Sauter , Ronald Simon , Phillip Stahl , Frederik Holst , Khawla Al-Kuraya , Christian Ruiz
- 申请人地址: DE Hamburg
- 专利权人: Universitatsklinikum Hamburg-Eppendorf
- 当前专利权人: Universitatsklinikum Hamburg-Eppendorf
- 当前专利权人地址: DE Hamburg
- 代理机构: Marshall, Gerstein & Borun LLP
- 优先权: EP06116106 20060626
- 国际申请: PCT/EP2007/056384 WO 20070626
- 国际公布: WO2008/000749 WO 20080103
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative breast disease as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative breast disease who is at risk of developing breast cancer. The invention also provides kits for performing the above methods.
公开/授权文献
- US20100086915A1 DETECTION OF ESR1 AMPLIFICATION IN BREAST CANCER 公开/授权日:2010-04-08
信息查询