发明授权
- 专利标题: Percutaneously absorptive ophthalmic preparation comprising olopatadine
- 专利标题(中): 包含奥洛他定的经皮吸收性眼用制剂
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申请号: US11988377申请日: 2006-07-07
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公开(公告)号: US08101654B2公开(公告)日: 2012-01-24
- 发明人: Akiharu Isowaki , Tomoko Nakajima , Akira Ohtori
- 申请人: Akiharu Isowaki , Tomoko Nakajima , Akira Ohtori
- 申请人地址: JP Osaka
- 专利权人: Senju Pharmaceutical Co., Ltd.
- 当前专利权人: Senju Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 国际申请: PCT/JP2006/314017 WO 20060707
- 国际公布: WO2007/007863 WO 20070118
- 主分类号: A01N43/02
- IPC分类号: A01N43/02 ; A01N43/40
摘要:
The present invention provides a percutaneously absorptive preparation for preventing or treating allergic eye disease, which comprises olopatadine or a salt thereof as an active ingredient. In addition, the present invention provides a method for preventing or treating allergic eye disease, which comprises applying a percutaneously absorptive preparation comprising olopatadine or a salt thereof to the skin surface including the skin surface of an eyelid, thereby casing transfer of a therapeutically effective amount of olopatadine or a salt thereof from the preparation to an anterior ocular segment through the skin of the eyelid rather than a systemic blood flow. The present preparation can exert a pharmacological effect over a prolonged period by a single application, as compared to conventional preparations such as eye drops.
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