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11 条记录 (耗时 0.015 秒)

    Percutaneously absorptive ophthalmic preparation comprising olopatadine
    1.
    发明授权
    Percutaneously absorptive ophthalmic preparation comprising olopatadine 有权
    包含奥洛他定的经皮吸收性眼用制剂

    公开(公告)号：US08101654B2

    公开(公告)日：2012-01-24

    申请号：US11988377

    申请日：2006-07-07

    申请人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    发明人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    IPC分类号： A01N43/02 ,  A01N43/40

    CPC分类号： A61K9/0014 ,  A61K9/0048

    摘要： The present invention provides a percutaneously absorptive preparation for preventing or treating allergic eye disease, which comprises olopatadine or a salt thereof as an active ingredient. In addition, the present invention provides a method for preventing or treating allergic eye disease, which comprises applying a percutaneously absorptive preparation comprising olopatadine or a salt thereof to the skin surface including the skin surface of an eyelid, thereby casing transfer of a therapeutically effective amount of olopatadine or a salt thereof from the preparation to an anterior ocular segment through the skin of the eyelid rather than a systemic blood flow. The present preparation can exert a pharmacological effect over a prolonged period by a single application, as compared to conventional preparations such as eye drops.

    摘要翻译： 本发明提供一种用于预防或治疗过敏性眼病的经皮吸收制剂，其包含奥洛他定或其盐作为活性成分。 此外，本发明提供了一种预防或治疗过敏性眼病的方法，其包括将包含奥洛他定或其盐的经皮吸收制剂施用于包括眼睑皮肤表面的皮肤表面，由此将治疗有效量 的奥洛他定或其盐从制剂通过眼睑的皮肤而不是全身血液流过眼前段。 与常规制剂如滴眼剂相比，本发明的制剂可以通过单次使用施用长时间的药理作用。

    OPHTHALMIC PERCUTANEOUS ABSORPTION TYPE PREPARATION
    2.
    发明申请
    OPHTHALMIC PERCUTANEOUS ABSORPTION TYPE PREPARATION 审中-公开
    OPHTHALMIC PERCUTANEOUS吸收式制备

    公开(公告)号：US20090318422A1

    公开(公告)日：2009-12-24

    申请号：US12310281

    申请日：2007-08-28

    申请人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    发明人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    IPC分类号： A61K31/55 ,  A61K31/44 ,  A61K31/335

    CPC分类号： A61K9/0048

    摘要： The present invention provides an ophthalmic percutaneous absorption type preparation containing an ophthalmic drug and a vasoconstrictor, which can increase the amount of the ophthalmic drug transferred through the eyelid to a topical area in the eye, particularly the anterior segment of the eye such as conjunctiva, lacrimal fluid, aqueous humor, cornea and the like by administration to the skin surface of an eyelid.

    摘要翻译： 本发明提供一种含有眼用药物和血管收缩剂的眼用经皮吸收型制剂，其可以将通过眼睑转移的眼药物的量增加到眼睛中的局部区域，特别是眼睛前段，例如结膜， 泪液，房水，角膜等，通过施用于眼睑的皮肤表面。

    Steam condenser
    3.
    发明授权
    Steam condenser 有权
    蒸汽冷凝器

    公开(公告)号：US07481264B2

    公开(公告)日：2009-01-27

    申请号：US11138664

    申请日：2005-05-27

    申请人： Toshihiro Yoshii ,  Shunichi Goshima ,  Yukio Takigawa ,  Tomoko Nakajima, legal representative ,  Yuuichi Nakajima, legal representative ,  Miyuki Nakajima, legal representative ,  Fumio Obara ,  Akira Nemoto ,  Shunji Kawano ,  Yuji Inoue

    发明人： Shoji Nakajima

    IPC分类号： F28B9/10

    CPC分类号： F28B1/02 ,  F28B9/10 ,  Y10S165/203

    摘要： A steam condenser which condenses steam exhausted from a steam turbine. Heat transfer tubes are arrayed below the steam turbine inside the container. Cooling medium flows inside the heat transfer tubes. The heat transfer tubes extend horizontally, and include at least two upper heat transfer tube groups and at least two lower heat transfer tube groups arranged with a gap between each other. Each heat transfer tube group is constituted by arraying heat transfer tubes like a grid. At a lower part between the lower heat transfer tube groups, a baffle plate which obstructs flow of steam extends horizontally. Between the upper and lower heat transfer tube groups, inter-tube-group inundation prevention plates extend horizontally. In each heat transfer tube group, an enclosure part extends to guide gas from the enclosure part to outside of the container through a gas extraction duct.

    摘要翻译： 一种蒸汽冷凝器，其将从蒸汽轮机排出的蒸汽冷凝。 传热管排列在容器内的汽轮机下方。 冷却介质在传热管内流动。 传热管水平延伸，并且包括至少两个上部传热管组和至少两个相互间有间隙布置的下部传热管组。 每个传热管组由诸如栅格的传热管排列构成。 在下部传热管组之间的下部，妨碍蒸汽流动的挡板水平延伸。 在上下传热管组之间，管间组防水板水平延伸。 在每个传热管组中，外壳部分延伸以通过气体抽出管将气体从外壳部分导引到容器外部。

    METHOD FOR HEAT-TREATING SILICON WAFER
    7.
    发明申请
    METHOD FOR HEAT-TREATING SILICON WAFER 审中-公开
    热处理硅砂的方法

    公开(公告)号：US20100009548A1

    公开(公告)日：2010-01-14

    申请号：US12438786

    申请日：2007-08-21

    申请人： Kozo Nakamura ,  Seiichi Shimura ,  Tomoko Nakajima

    发明人： Kozo Nakamura ,  Seiichi Shimura ,  Tomoko Nakajima

    IPC分类号： H01L21/26

    CPC分类号： H01L21/324 ,  H01L21/3225 ,  H01L21/67115

    摘要： Provided is a heat treatment method wherein generation of slip dislocation in silicon wafer RTP is suppressed, in order to solve a problem of not sufficiently suppressing generation of slip dislocation of silicon wafers in conventional RTP. A step is provided for suspending temperature rising for 10 seconds or longer at a temperature in a range of over 700° C. to below 950° C., so as to prevent generation of slip dislocation during rapid heating, at least at a silicon wafer portion that contacts with a supporting section of a rapid heating apparatus or at a portion on the outermost circumference section of the silicon wafer.

    摘要翻译： 提供了一种热处理方法，其中抑制了硅晶片RTP中的滑移位错的产生，以解决在常规RTP中不能充分抑制硅晶片的滑移位错产生的问题。 提供了一个步骤，用于在超过700℃至低于950℃的温度下将温度上升10秒或更长，以防止在快速加热期间产生滑移位错，至少在硅晶片 与快速加热装置的支撑部分或硅晶片的最外周部分的部分接触的部分。

    Percutaneously Absorptive Ophthalmic Preparation Comprising Olopatadine
    8.
    发明申请
    Percutaneously Absorptive Ophthalmic Preparation Comprising Olopatadine 有权
    包含奥洛他定的经皮吸收性眼科制剂

    公开(公告)号：US20090209632A1

    公开(公告)日：2009-08-20

    申请号：US11988377

    申请日：2006-07-07

    申请人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    发明人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    IPC分类号： A61K31/335 ,  A61P27/02

    CPC分类号： A61K9/0014 ,  A61K9/0048

    摘要： The present invention provides a percutaneously absorptive preparation for preventing or treating allergic eye disease, which comprises olopatadine or a salt thereof as an active ingredient. In addition, the present invention provides a method for preventing or treating allergic eye disease, which comprises applying a percutaneously absorptive preparation comprising olopatadine or a salt thereof to the skin surface including the skin surface of an eyelid, thereby casing transfer of a therapeutically effective amount of olopatadine or a salt thereof from the preparation to an anterior ocular segment through the skin of the eyelid rather than a systemic blood flow. The present preparation can exert a pharmacological effect over a prolonged period by a single application, as compared to conventional preparations such as eye drops.

    摘要翻译： 本发明提供一种用于预防或治疗过敏性眼病的经皮吸收制剂，其包含奥洛他定或其盐作为活性成分。 此外，本发明提供了一种预防或治疗过敏性眼病的方法，其包括将包含奥洛他定或其盐的经皮吸收制剂施用于包括眼睑皮肤表面的皮肤表面，由此将治疗有效量 的奥洛他定或其盐从制剂通过眼睑的皮肤而不是全身血液流过眼前段。 与常规制剂如滴眼剂相比，本发明的制剂可以通过单次使用施用长时间的药理作用。

    Percutaneously Absorptive Ophthalmic Preparation Comprising Epinastine
    9.
    发明申请
    Percutaneously Absorptive Ophthalmic Preparation Comprising Epinastine 审中-公开
    包含依诺斯汀的经皮吸收性眼科制剂

    公开(公告)号：US20090143359A1

    公开(公告)日：2009-06-04

    申请号：US11988390

    申请日：2006-07-07

    申请人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    发明人： Akiharu Isowaki ,  Tomoko Nakajima ,  Akira Ohtori

    IPC分类号： A61K31/55

    CPC分类号： A61K9/7023 ,  A61K9/0048 ,  A61K9/06 ,  A61K9/107

    摘要： The present invention provides a percutaneously absorptive preparation for preventing or treating allergic eye disease, which comprises epinastine or a salt thereof as an active ingredient. In addition, the present invention provides a method for preventing or treating allergic eye disease, which comprises applying a percutaneously absorptive preparation comprising epinastine or a salt thereof to the skin surface including the skin surface of an eyelid, thereby causing transfer of a therapeutically effective amount of epinastine or a salt thereof from the preparation to an anterior ocular segment through the skin of the eyelid rather than a systemic blood flow. The present preparation can exert a pharmacological effect over a prolonged period by a single application, as compared to conventional preparations such as eye drops.

    摘要翻译： 本发明提供一种用于预防或治疗过敏性眼病的经皮吸收制剂，其包含依波他汀或其盐作为活性成分。 此外，本发明提供一种预防或治疗过敏性眼病的方法，其包括将包含依托斯汀或其盐的经皮吸收制剂施用于包括眼睑皮肤表面的皮肤表面，从而导致治疗有效量的转移 的依帕斯他汀或其盐从制剂到眼前段，通过眼睑的皮肤而不是全身血流。 与常规制剂如滴眼剂相比，本发明的制剂可以通过单次使用施用长时间的药理作用。