发明授权
- 专利标题: Treatment of neoplasms with viruses
- 专利标题(中): 用病毒治疗肿瘤
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申请号: US11698947申请日: 2007-01-29
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公开(公告)号: US08105578B2公开(公告)日: 2012-01-31
- 发明人: Michael S. Roberts , Robert M. Lorence , William S. Groene , Harvey Rabin , Reid W. von Borstel
- 申请人: Michael S. Roberts , Robert M. Lorence , William S. Groene , Harvey Rabin , Reid W. von Borstel
- 申请人地址: US MD Gaithersburg
- 专利权人: Wellstat Biologics Corporation
- 当前专利权人: Wellstat Biologics Corporation
- 当前专利权人地址: US MD Gaithersburg
- 代理商 Douglas A. Golightly
- 主分类号: A01N63/00
- IPC分类号: A01N63/00 ; C12N7/00
摘要:
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
公开/授权文献
- US20080057037A1 Treatment of neoplasms with viruses 公开/授权日:2008-03-06
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