发明授权
US08105785B2 Mylks as modifiers of branching morphogenesis and methods of use
失效
Mylks作为分支形态发生和使用方法的修饰剂
- 专利标题： Mylks as modifiers of branching morphogenesis and methods of use
- 专利标题（中）： Mylks作为分支形态发生和使用方法的修饰剂
-
申请号： US10556637申请日： 2004-06-18
-
公开(公告)号： US08105785B2公开(公告)日： 2012-01-31
- 发明人: Gregory D. Plowman , Felix D. Karim , Candace Swimmer , Hinrich Alexander Habeck , Thomas I. Koblizek , Stefan Schulte-Merker , Ulrike Eisenmann , Gordon Mark Stott , Torsten Trowe , Andreas Michael Vogel , Joerg Heinrich Odenthal , Jochen Konrad Scheel , Torsten Tilmann Will , Yinsheng Jin , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人： Gregory D. Plowman , Felix D. Karim , Candace Swimmer , Hinrich Alexander Habeck , Thomas I. Koblizek , Stefan Schulte-Merker , Ulrike Eisenmann , Gordon Mark Stott , Torsten Trowe , Andreas Michael Vogel , Joerg Heinrich Odenthal , Jochen Konrad Scheel , Torsten Tilmann Will , Yinsheng Jin , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人地址： US CA South San Francisco
- 专利权人： Exelixis, Inc.
- 当前专利权人： Exelixis, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 国际申请： PCT/US2004/019485 WO 20040618
- 国际公布： WO2005/003372 WO 20050113
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/53
摘要：
Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MYLK are provided.