Invention Grant
- Patent Title: Prodrugs activated by RNA-dependent DNA-polymerases
- Patent Title (中): 通过RNA依赖性DNA聚合酶活化的前体药物
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Application No.: US11659269Application Date: 2005-08-02
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Publication No.: US08110676B2Publication Date: 2012-02-07
- Inventor: Ivano Bertini , Claudio Luchinat , Alessandro Quattrone , Massimo Calamante , Alessandro Mordini
- Applicant: Ivano Bertini , Claudio Luchinat , Alessandro Quattrone , Massimo Calamante , Alessandro Mordini
- Applicant Address: IT Sesto Fiorentino
- Assignee: Protera S.R.L.
- Current Assignee: Protera S.R.L.
- Current Assignee Address: IT Sesto Fiorentino
- Agency: Clark & Elbing LLP
- Priority: ITFI2004A0173 20040803
- International Application: PCT/EP2005/053765 WO 20050802
- International Announcement: WO2006/013203 WO 20060209
- Main IPC: C07H19/20
- IPC: C07H19/20
Abstract:
The invention provides prodrugs activated by RNA-dependent DNA-polymerases, and methods for treating hematological tumors, blood, and blood derivatives from patients affected by retroviral infections by administering the prodrugs. The invention also provides methods for the preparation of pharmaceutical compositions containing the prodrugs.
Public/Granted literature
- US20080300215A1 Prodrugs Activated by Rna-Dependent Dna-Polymerases Public/Granted day:2008-12-04
Information query
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