发明授权
US08114398B2 EGLN2 variants and use thereof in preventing or treating thromboembolic disorders and coronary heart disease 失效
EGLN2变体及其在预防或治疗血栓栓塞性疾病和冠心病中的用途

  • 专利标题: EGLN2 variants and use thereof in preventing or treating thromboembolic disorders and coronary heart disease
  • 专利标题(中): EGLN2变体及其在预防或治疗血栓栓塞性疾病和冠心病中的用途
  • 申请号: US12089627
    申请日: 2006-09-30
  • 公开(公告)号: US08114398B2
    公开(公告)日: 2012-02-14
  • 发明人: Detlef KozianMatthias Herrmann
  • 申请人: Detlef KozianMatthias Herrmann
  • 申请人地址: FR Paris
  • 专利权人: Sanofi-Aventis
  • 当前专利权人: Sanofi-Aventis
  • 当前专利权人地址: FR Paris
  • 代理商 J. Darrell Fontenot
  • 优先权: DE102005048898 20051012
  • 国际申请: PCT/EP2006/009518 WO 20060930
  • 国际公布: WO2007/042166 WO 20070419
  • 主分类号: A61K38/46
  • IPC分类号: A61K38/46 C12N15/00 C12N9/14 C12N15/11
EGLN2 variants and use thereof in preventing or treating thromboembolic disorders and coronary heart disease
摘要:
The present invention refers to human EGLN2 variants having at position 58 of the amino acid sequence a serine or a leucine and their use in the prevention or treatment of thromboembolic or coronary heart diseases, in particular stroke, prolonged reversible ischemic neurological deficit (PRIND), transitoric ischemic attack (TIA), myocardial infarction and/or early myocardial infarction.
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