发明授权
- 专利标题： Linear and cyclic melanocortin receptor-specific peptidomimetics
- 专利标题（中）： 线性和环状黑皮质素受体特异性肽模拟物
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申请号： US12244880申请日： 2008-10-03
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公开(公告)号： US08114844B2公开(公告)日： 2012-02-14
- 发明人: Shubh D. Sharma , Margarita Bastos , Wei Yang
- 申请人： Shubh D. Sharma , Margarita Bastos , Wei Yang
- 申请人地址： US NJ Cranbury
- 专利权人： Palatin Technologies, Inc.
- 当前专利权人： Palatin Technologies, Inc.
- 当前专利权人地址： US NJ Cranbury
- 代理商 Stephen A. Slusher
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; A61K38/08 ; C07D403/00
摘要：
Linear and cyclic peptidomimetics which bind to one or more melanocortin receptors are provided, which peptidomimetics include at least one ring-constrained amino acid surrogate of formula I: where R1, R2, R3, R4, R5, R6, R7, R8, and y are as defined in the specification, together with methods for synthesizing ring-constrained amino acid surrogates of formula I and peptidomimetics incorporating the same, and methods of use of peptidomimetics in the treatment of various diseases, syndromes and conditions.
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