发明授权
- 专利标题： Naphthylacetic acids
- 专利标题（中）： 萘乙酸
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申请号： US12614478申请日： 2009-11-09
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公开(公告)号： US08124629B2公开(公告)日： 2012-02-28
- 发明人: Fariborz Firooznia , Paul Gillespie , Tai-An Lin , Eric Mertz , Achyutharao Sidduri , Sung-Sau So , Jenny Tan , Kshitij Chhabilbhai Thakkar
- 申请人： Fariborz Firooznia , Paul Gillespie , Tai-An Lin , Eric Mertz , Achyutharao Sidduri , Sung-Sau So , Jenny Tan , Kshitij Chhabilbhai Thakkar
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Dennis P. Tramaloni; Brian C. Remy
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/192 ; C07D211/54 ; C07C63/64
摘要：
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
公开/授权文献
- US20100137250A1 NAPHTHYLACETIC ACIDS 公开/授权日：2010-06-03
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