Invention Grant
US08128932B2 Anti-VEGFR monoclonal antibody, method of making and uses thereof
有权
抗VEGFR单克隆抗体,其制备方法和用途
- Patent Title: Anti-VEGFR monoclonal antibody, method of making and uses thereof
- Patent Title (中): 抗VEGFR单克隆抗体,其制备方法和用途
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Application No.: US12542239Application Date: 2009-08-17
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Publication No.: US08128932B2Publication Date: 2012-03-06
- Inventor: Jie Tong , Jian Min Fang , Wenqing Wu , Bin Zhang , Desheng Jiang
- Applicant: Jie Tong , Jian Min Fang , Wenqing Wu , Bin Zhang , Desheng Jiang
- Applicant Address: CN Shanghai
- Assignee: Shanghai Aosaiersi Biotech Co., Ltd.
- Current Assignee: Shanghai Aosaiersi Biotech Co., Ltd.
- Current Assignee Address: CN Shanghai
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/00 ; C07K16/28

Abstract:
The subject invention is directed to a VEGFR2 (vascular endothelial growth factor receptor II) monoclonal antibody (mAb), and the amino acid sequence of the heavy chain and the light chain of the mAb. The invention is also directed to methods for making the VEGFR2 mAb, and methods of using the mAb to inhibit angiogenesis and treat various conditions such as tumor and retinal diseases.
Public/Granted literature
- US20110038874A1 ANTI-VEGFR MONOCLONAL ANTIBODY, METHOD OF MAKING AND USES THEREOF Public/Granted day:2011-02-17
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