Method of managing interaction between a host subsystem and a peripheral device. Roughly described, the peripheral device writes an event into an individual event queue, and in conjunction therewith, also writes a wakeup event into an intermediary event queue. The wakeup event identifies the individual event queue. The host subsystem, in response to retrieval of the wakeup event from the intermediary event queue, activates an individual event handler to consume events from the individual event queue.