发明授权
US08134025B2 Method of fabricating mesocrystals of organic and organo-metallic compounds
有权
制备有机和有机金属化合物的晶体的方法
- 专利标题: Method of fabricating mesocrystals of organic and organo-metallic compounds
- 专利标题(中): 制备有机和有机金属化合物的晶体的方法
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申请号: US12076253申请日: 2008-03-14
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公开(公告)号: US08134025B2公开(公告)日: 2012-03-13
- 发明人: Tu Lee , Chyong-Wen Zhang
- 申请人: Tu Lee , Chyong-Wen Zhang
- 申请人地址: TW Taoyuan County
- 专利权人: National Central University
- 当前专利权人: National Central University
- 当前专利权人地址: TW Taoyuan County
- 代理机构: Jackson IPG PLLC
- 代理商 Demian K. Jackson
- 优先权: TW96129464A 20070809
- 主分类号: C07C53/134
- IPC分类号: C07C53/134
摘要:
The present invention fabricates mesocrystals of organic and organo-metallic compounds. Supersaturated solutions are made with different sums of an organic or organo-metallic compound and the organic or organo-metallic compound is added with an excipient. Through a water bath, mesocrystals are obtained from the supersaturated solutions with well-faceted nucleation and growth. Different polymorphisms are induced with different ratios of enantiomers. And the dissolution rate for fabricating the API is enhanced.
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