An image capture system for recording X-ray images in real time is disclosed. The image capture system includes an image pickup device, a sensing module and a surgical navigation device. The sensing module is used to detect the on/off status of the image pickup device. While the image pickup device is turned on to capture an X-ray image, the sensing module transmits a notification signal to the surgical navigation device. After receiving the notification signal, the surgical navigation device records the X-ray image captured by the image pickup device and the relative position between the image pickup device and the patient in real time. Thus, the real-time recording of the relative position between the image pickup device and the patient will prevent inaccurate image reading that occurs when the patient's position and image pickup device shift after the X-ray image has been captured.