Disclosed is an imaging system including a source generating an x-ray beam, a detector array receiving the x-ray beam and generating projection data, a translatable table configured for disposal of an object thereon and operable to translate in relation to the source and the detector array, the source and the detector array rotating about the translatable table to scan the object, and an image reconstructor electrically coupled to the detector array and configured to reconstruct an image in response to the projection data via an iterative reconstruction technique configured to perform a targeted statistical reconstruction.