Invention Grant
- Patent Title: Quinoline derivatives as PI3 kinase inhibitors
- Patent Title (中): 喹啉衍生物作为PI3激酶抑制剂
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Application No.: US12121891Application Date: 2008-05-16
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Publication No.: US08138347B2Publication Date: 2012-03-20
- Inventor: Steven David Knight , Stanley J. Schmidt
- Applicant: Steven David Knight , Stanley J. Schmidt
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Tony W. Peng; Edward R. Gimmi
- Main IPC: C07D285/24
- IPC: C07D285/24 ; C07D401/14 ; C07D413/14
Abstract:
Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
Public/Granted literature
- US20080300239A1 QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS Public/Granted day:2008-12-04
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