Invention Grant
US08143277B2 Method of using compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity 失效
使用具有2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物的方法

Method of using compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
Abstract:
This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8a, R8b, W, a, b, c and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
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