Invention Grant
US08143277B2 Method of using compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
失效
使用具有2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物的方法
- Patent Title: Method of using compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
- Patent Title (中): 使用具有2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物的方法
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Application No.: US12479017Application Date: 2009-06-05
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Publication No.: US08143277B2Publication Date: 2012-03-27
- Inventor: Mathai Mammen , Trevor Mischki , Adam Hughes , YuHua Ji
- Applicant: Mathai Mammen , Trevor Mischki , Adam Hughes , YuHua Ji
- Applicant Address: US CA South San Francisco
- Assignee: Theravance, Inc.
- Current Assignee: Theravance, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K31/445 ; A61P11/08

Abstract:
This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8a, R8b, W, a, b, c and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
Public/Granted literature
- US20090239904A1 COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY Public/Granted day:2009-09-24
Information query
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