With a nonparametric G-Rake receiver, combining weights may be determined using a nonparametric mechanism in multiple-input, multiple-output (MIMO) scenarios. In an example embodiment, a method for a receiving device having a nonparametric G-Rake receiver entails calculating an impairment covariance matrix and determining combining weights. More specifically, the impairment covariance matrix is calculated based on a pilot channel using a nonparametric mechanism in a MIMO scenario in which a code-reuse interference term exists. The combining weights are determined for the nonparametric G-Rake receiver responsive to the impairment covariance matrix and by accounting for the code-reuse interference term.