Invention Grant
- Patent Title: Isoindolinone derivatives having inhibitory activity against T-type calcium channel and method for preparation thereof
- Patent Title (中): 对T型钙通道具有抑制活性的异吲哚啉酮衍生物及其制备方法
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Application No.: US12256701Application Date: 2008-10-23
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Publication No.: US08148402B2Publication Date: 2012-04-03
- Inventor: Yong Seo Cho , Ae Nim Pae , Hyunah Choo , Jae Kyun Lee , You Na Oh , Seon Hee Seo , Hyewhon Rhim
- Applicant: Yong Seo Cho , Ae Nim Pae , Hyunah Choo , Jae Kyun Lee , You Na Oh , Seon Hee Seo , Hyewhon Rhim
- Applicant Address: KR Seoul
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR Seoul
- Agency: Ladas & Parry LLP
- Priority: KR10-2008-0065522 20080707
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D401/02

Abstract:
Disclosed are isoindolinone derivatives, represented by Chemical Formula 1, having inhibitory activity against T-type calcium channels, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient. wherein R1˜R6 are as defined in the specification.
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